01
V Spa at The Venetian Macao
CotaiDaily 12:00–04:00Bookable online
The only hotel spa on this list with genuinely late hours — and the best quality-to-convenience option after midnight on the Strip. Klook 60-minute packages from around US$77; buy the voucher earlier in the day and reserve a late slot with the spa.
02
Foot Recreation (足之樂)
Taipa (Rua do Cunha) and Peninsula (Av. da Amizade)Open 24 hours, 365 days
Foot baths, foot massage and full-body aromatherapy around the clock. Vouchers about MOP 240–250 for 60 minutes; walk-ins welcome. 18+ only.
03
Thai Xi Spa (formerly Thailand Palace)
20F, Grand Emperor Hotel, PeninsulaOpen 24 hours, 365 days
Thai massage through the night in the city centre — 30-minute head/shoulder/neck, 60-minute aromatherapy oil, 90-minute oil SPA with bubble bath. Confirm current prices at booking; walk-ins welcome.